Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.
Within tissues, cells are embedded in complex, three-dimensional structures known as the extracellular matrix. Their biomechanical interactions play a crucial role in numerous biological processes.
Growing from a single cell into a complex organism with specialized tissues and organs requires a complex and coordinated process. But the mechanical signals that guide tissue and organ ...
Rotator cuff tears often heal with stiff, dysfunctional scar tissue, limiting recovery. A new study reveals why tendon ...
In cell and animal models of amyotrophic lateral sclerosis (ALS), the expression of toxic dipeptides in neurons led to changes in the extracellular matrix (ECM) as a protective response. The authors ...
Hypertrophic scars remain one of the most persistent challenges in wound healing, often resulting in excessive fibrosis, disfigurement, and long-term functional impairment. Researchers now report a ...
Ultrasound-mediated nanobubbles improve cancer therapy by softening tumors, enhancing lipid nanoparticle distribution, and ...