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Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A—all-trans retinoic ...

For years, scientists have puzzled over the paradoxical relationship between cancer and retinoids, the metabolites that animals and people produce when their bodies break down vitamin A. About 40 ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic ...

New stem cell-based embryo model reveals previously unknown communication between early tissues that become the spine and muscles in the central part of the body. From the moment an embryo starts to ...

Introduction: Adult Cardiomyocytes (CMs) are post-mitotic cells, hence cardiac insults usually progress to heart failure. In contrary, spontaneously cycling CMs are a distinct population in the ...

APOLLO: Optimizing the Treatment of High-Risk Acute Promyelocytic Leukemia With All-Trans Retinoic Acid and Arsenic Trioxide While Minimizing the Role of Chemotherapy The following represents ...

Aldehyde dehydrogenase 1 (ALDH1) is an important aldehyde-metabolizing enzyme that plays a key role in various biological processes, such as regulating cellular growth, modulating retinoic acid (RA) ...

Researchers demonstrate how the co-exposure of bisphenol A and retinoic acid (RA) potentiate the effect of RA signaling in early development. Synthetic chemicals and plastics are useful and ...