Reconstructed particle-on-a-string 3D genomes of Brassica rapa. (a) 3D organization with expanded views of the separate chromosome territories. (b) Spatial distribution of telomeres and centromeres of ...

This image depicts the detection of structural variants (SVs) at low sequencing coverage in both unique and repetitive regions by genomic proximity mapping (GPM), compared with other SV-calling ...

Standard laboratory tests can fail to detect many disease-causing DNA changes. Now, a novel 3D chromosome mapping method can reliably reveal these hidden structural variants and lead to new ...

Advances in 3D genomics and multiomics are enabling scientists to uncover disease mechanisms hidden in the human genome's noncoding regions.