A new research paper titled "Sirtuin 6 activation rescues the age-related decline in DNA damage repair in primary human chondrocytes" has been published in Aging. While advanced age is widely ...

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Sirtuin 6 activation rescues the ...

Key molecular regulators: Sirtuins are NAD+-dependent enzymes that link energy metabolism to gene regulation, stress responses, and mitochondrial health. Impact on aging: They preserve genomic ...

Researchers present novel therapeutics that rejuvenate a previously undruggable mitochondrial regulator of aging through a new mode of enzyme activation. Leveraging a newly identified biophysical ...

“[...] the biological mechanisms linking aging and osteoarthritis prevalence remain largely unknown.” “In this study, we use irradiation as an acute model of ...