Oncotarget published "Role for Fgr and Numb in retinoic acid-induced differentiation and G0 arrest of non-APL AML cells" which reported that retinoic acid is a fundamental regulator of cell cycle and ...

Researchers demonstrate how the co-exposure of bisphenol A and retinoic acid (RA) potentiate the effect of RA signaling in early development. Synthetic chemicals and plastics are useful and ...

Figure 6: Cell cycle analysis of HL-60 WT and FGR O.E cells. DNA histograms show FGR transfectants were enriched for relative number of G1/0 cells compared to the wt cells. Wild-type and FGR O.E cell ...

Synthetic chemicals and plastics are useful and indispensable in our lives. On the other hand, the world is grappling with plastic pollution-clogging oceans, threatening wildlife, and leaching into ...

According to new research, T cells have a nuclear receptor doing something very odd—but very important—to help them fight pathogens and destroy cancer cells. This receptor, called retinoic acid ...

Scientists at the Princeton University Branch of the Ludwig Institute for Cancer Research have identified novel mechanisms by which a metabolic derivative of vitamin A-all-trans retinoic ...

A new study published in Nature Communications heralded some fascinating findings on the future of drug development for neuroblastoma treatment. Cancer that forms in developing nerve cells, ...

Why retinoic acid is effective in this setting but not against primary tumors, has been speculated about for nearly 50 years. Scientists resolved the mystery, showing the drug 'hijacks' a normal ...