The UPLC system was configured with an Acquity Premier Oligonucleotide C18 column (1.7 µm, 2.1 × 50 mm). The aqueous and ...

Del-desiran reduced DMPK mRNA levels, but led to two serious adverse events ...

Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by enabling improved scalability and purity.

OSAKA, Japan--(BUSINESS WIRE)--In response to the rapid market expansion of oligonucleotide therapeutics that have potential to treat both common and intractable diseases, Nitto Denko Corporation ...

As Chief Editor of one of the two journals in which Biopharma Dealmakers appears, I have a keen interest in the process of translating biomedical research into new drugs, including the partnerships ...

Strategic investments in ASO and siRNA platforms, coupled with breakthrough delivery technologies, position oligonucleotide ...

Knowledge of gene function is required to utilize sequence information to develop new drugs to treat disease. In vitro techniques, such as antisense oligonucleotides (AS-ODNs) 1,2,3, ribozymes 4,5, ...

New York, USA, Aug. 28, 2025 (GLOBE NEWSWIRE) -- Antisense Oligonucleotide Therapeutics Clinical Trial Pipeline Appears Robust With 70+ Key Pharma Companies Actively Working in the Domain | ...

The use of oligonucleotides as therapeutic agents is of great interest, particularly when it comes to siRNA and antisense oligonucleotides. However, the difficulty of targeting the right organ and ...

Oligonucleotide therapeutics make up a small but rapidly growing segment of the overall global drug pipeline, with 245 programs currently in development today. While only one approved oligo ...

When the drug fomivirsen was approved by the FDA in 1998 for the treatment of cytomegalovirus retinitis in patients with HIV/AIDs, it was hailed as a milestone in drug discovery because it was the ...