Homologous recombination is a high-fidelity pathway responsible for the repair of DNA double-strand breaks and the maintenance of genome stability. The process initiates with detection of a break ...
A double-strand break (DSB) is a type of DNA damage where both strands of the DNA helix are cut or broken at the same location, causing a complete discontinuity in the DNA molecule. Unrepaired or ...
Meiotic recombination is a specialised process in which programmed DNA double-strand breaks initiate the exchange of genetic material between homologous chromosomes. This exchange forms crossovers ...
A research group led by Prof. Guo Caixia from the Beijing Institute of Genomics of the Chinese Academy of Sciences (CAS) and Tang Tie-Shan from the Institute of Zoology of CAS have discovered that ...