Researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes inside the cell. The findings lead to a deeper ...

Carfilzomib prevented BCMA degradation, increased target density, and improved CAR T susceptibility by ~26%–28% in vitro, while enhancing xenograft antitumor activity without worsening T-cell ...

Scientists have long known that cellular membranes vary in thickness, but measuring those differences inside actual cells has been out of reach. Subscribe to our newsletter for the latest sci-tech ...

A surprising new function of essential hearing proteins may explain why some genetic mutations and common antibiotics lead to permanent deafness.

Scientists link TMC protein membrane disruption to hearing loss, showing how mutations, drugs and noise trigger hair cell ...

How flu viruses enter cells has been directly observed thanks to a new microscopy technique with the potential to revolutionize research on membrane biology, virus–host interactions and drug discovery ...