Autoimmune polyendocrine syndrome type 1 (APS-1) responded to ruxolitinib (Jakafi) in a small study, researchers said, offering hope that one drug can relieve most of the symptoms of this rare but ...

Cross-sections of lungs from mice with the gene deficiency that causes APS-1, showing damaged tissue in mice not administered ruxolitinib (left) and healthy tissue in mice administered ruxolitinib ...

Autoimmune Addison's disease (AAD) results from the immune-mediated destruction of adrenocortical cells. AAD is a major component of the autoimmune polyendocrine syndromes type 1 (APS 1) and type 2.

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers ...

A new study led by researchers at the National Institutes of Health’s (NIH) National Institute of Allergy and Infectious Diseases (NIAID) demonstrates a drug approved to treat certain autoimmune ...

The Nature Index 2026 Research Leaders reveal the leading institutions and countries/territories in the natural sciences, health sciences, applied sciences and social sciences, according to their ...

Featuring articles on aficamten for obstructive hypertrophic cardiomyopathy; early blood-pressure reduction in acute stroke; interferon-γ in autoimmune polyendocrine syndrome type 1; video ...

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1). Researchers ...